Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582989 | 0.90 | L3MBTL1 (0.53) | L3MBTL1MAPTALDH1A1HTTMAPK1 | |
| SCHEMBL4780609 | 0.78 | MAOA (0.44) | MAPTALDH1A1HTTMAPK1MEN1 | |
| SCHEMBL4798159 | 0.77 | P4HB (0.51) | P4HB | |
| SCHEMBL4796301 | 0.71 | TGM2 (0.50) | L3MBTL1MAPTALDH1A1P4HBKDM4E | |
| SCHEMBL20456543 | 0.70 | L3MBTL1 (0.68) | ACHEL3MBTL1MAPTALDH1A1HTT | |
| SCHEMBL4781996 | 0.70 | AR (0.43) | P4HB | |
| SCHEMBL15266902 | 0.67 | L3MBTL1 (0.63) | L3MBTL1MAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL8073094 | 0.67 | AR (0.58) | P4HB | |
| SCHEMBL27976453 | 0.67 | AKR1C3 (0.85) | L3MBTL1MAPTALDH1A1HTTMAPK1 | |
| SCHEMBL4797029 | 0.66 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015265-A1 | ANTHRACEN DERIVATIVES AND THEIR USE FOR THE TREATMENT OF BENIGN AND MALIGNANT TUMOROUS DISEASES | ÆTERNA ZENTARIS GMBH (DE) | 2008-02-07 | — | — | WO | claimed |
| WO-2008015265-A1 | ANTHRACEN DERIVATIVES AND THEIR USE FOR THE TREATMENT OF BENIGN AND MALIGNANT TUMOROUS DISEASES | ÆTERNA ZENTARIS GMBH (DE) | 2008-02-07 | — | — | WO | disclosed |