Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | DDT | P30046 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780945 | 0.90 | DDT (0.33) | DRD2DRD4DRD3DDTNR1I2 | |
| SCHEMBL4783718 | 0.84 | LMNA (0.36) | DDTNR1I2 | |
| SCHEMBL4779766 | 0.83 | NR1I2 (0.41) | NR1I2 | |
| SCHEMBL4778554 | 0.81 | DDT (0.42) | DRD2DRD4DRD3DDTNR1I2 | |
| SCHEMBL4799754 | 0.81 | MAPK14 (0.37) | DDTNR1I2 | |
| SCHEMBL4780603 | 0.79 | DRD2 (0.38) | DRD2DRD4DRD3DDT | |
| SCHEMBL4778561 | 0.77 | DDT (0.45) | DDTNR1I2 | |
| SCHEMBL4955400 | 0.77 | BRAF (0.42) | — | |
| SCHEMBL4781910 | 0.76 | GSK3A (0.33) | DDTNR1I2 | |
| SCHEMBL4783352 | 0.75 | MAPK14 (0.36) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |