Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780940 | 0.90 | DRD2 (0.34) | DDTDRD2DRD4DRD3NR1I2 | |
| SCHEMBL4783723 | 0.84 | LMNA (0.35) | DDTLMNAMAPTMEN1KMT2A | |
| SCHEMBL4779770 | 0.83 | NR1H4 (0.39) | DDTLMNAPOLBNR1I2 | |
| SCHEMBL4799766 | 0.81 | DDT (0.32) | DDTNR1I2 | |
| SCHEMBL4778561 | 0.81 | DDT (0.45) | DDTALDH1A1NPC1RAB9ANR1I2 | |
| SCHEMBL4730567 | 0.79 | TRPV1 (0.40) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4778554 | 0.79 | DDT (0.42) | DDTDRD2DRD4DRD3NR1I2 | |
| SCHEMBL4780603 | 0.76 | DRD2 (0.38) | DDTDRD2DRD4DRD3LMNA | |
| SCHEMBL4781910 | 0.76 | GSK3A (0.33) | DDTNR1I2 | |
| SCHEMBL4783359 | 0.76 | MAPK14 (0.35) | KMT2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |