Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778369 | 0.79 | NOTUM (0.40) | ALOX15DRD2GAA | |
| SCHEMBL4776044 | 0.78 | RORC (0.41) | SLC6A2SLC6A4UBE2MDCUN1D1CNR2 | |
| SCHEMBL4779434 | 0.78 | ADRA1D (0.48) | SLC6A2SLC6A4DRD2HTR7ADRA1A | |
| SCHEMBL4778958 | 0.78 | ADRA1D (0.48) | SLC6A2SLC6A4DRD2HTR7ADRA1A | |
| SCHEMBL14820140 | 0.78 | KMT2A (0.41) | SLC6A2SLC6A4DRD2 | |
| SCHEMBL18484463 | 0.78 | KMT2A (0.41) | SLC6A2SLC6A4DRD2 | |
| SCHEMBL7867642 | 0.78 | KMT2A (0.41) | SLC6A2SLC6A4DRD2 | |
| SCHEMBL4781028 | 0.76 | KDM4E (0.43) | ADRA1A | |
| SCHEMBL4780332 | 0.76 | CHRM4 (0.38) | DRD2UBE2MDCUN1D1GAASLC6A3 | |
| SCHEMBL4774664 | 0.75 | ADRA1D (0.38) | SLC6A2SLC6A4HTR1ADRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |