Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781031 | 0.82 | GAA (0.40) | RORCBCHE | |
| SCHEMBL4774183 | 0.81 | NPC1 (0.37) | RORCUBE2MDCUN1D1 | |
| SCHEMBL4778295 | 0.81 | SIGMAR1 (0.46) | CNR2 | |
| SCHEMBL4780977 | 0.78 | ALOX15 (0.38) | CNR2SLC6A2SLC6A4UBE2MDCUN1D1 | |
| SCHEMBL4780839 | 0.78 | SLC6A2 (0.44) | SLC6A2SLC6A4BCHE | |
| SCHEMBL4775240 | 0.76 | MEN1 (0.41) | RORCUBE2MDCUN1D1 | |
| SCHEMBL18484463 | 0.75 | KMT2A (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL14820140 | 0.75 | KMT2A (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL7867642 | 0.75 | KMT2A (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL4779333 | 0.74 | CHRM4 (0.39) | UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |