Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.35 |
| ▸ | DDT | P30046 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ACSL5 | Q9ULC5 | 1/20 | 0.32 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907955 | 0.88 | ESRRA (0.38) | MIFACKR3DDTCNR2CYP2C9 | |
| SCHEMBL14292741 | 0.86 | MIF (0.38) | MIFACKR3DDTCNR2NOTUM | |
| SCHEMBL1404674 | 0.83 | MIF (0.47) | MIFACKR3DDTCNR2 | |
| SCHEMBL4780603 | 0.82 | DRD2 (0.38) | MIFACKR3DDTCNR2NOTUM | |
| SCHEMBL4782176 | 0.82 | BRAF (0.45) | MAPK11MAPK14 | |
| SCHEMBL4782660 | 0.79 | NR1I2 (0.42) | MIFDDTMAPK14KLKB1 | |
| SCHEMBL4784135 | 0.79 | CYP1A2 (0.48) | CYP2C9 | |
| SCHEMBL4781910 | 0.76 | GSK3A (0.33) | DDTCYP2C9MAPK14 | |
| SCHEMBL4778554 | 0.76 | DDT (0.42) | DDT | |
| SCHEMBL4783370 | 0.76 | DDT (0.38) | MIFDDTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |