Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783374 | 0.91 | DDT (0.42) | DDTKDM4EMIFNPSR1GPR142 | |
| SCHEMBL14292741 | 0.77 | MIF (0.38) | DDTCNR2MIF | |
| SCHEMBL4779766 | 0.77 | NR1I2 (0.41) | — | |
| SCHEMBL4781668 | 0.76 | MIF (0.39) | DDTCNR2MIF | |
| SCHEMBL4779207 | 0.76 | NR1I2 (0.38) | DDTCNR2MIF | |
| SCHEMBL4779575 | 0.75 | ACKR3 (0.34) | DDTBRAF | |
| SCHEMBL4783994 | 0.75 | EGFR (0.33) | DDTMIF | |
| SCHEMBL4779770 | 0.74 | NR1H4 (0.39) | DDTKDM4E | |
| SCHEMBL4783530 | 0.74 | ACKR3 (0.34) | DDTBRAF | |
| SCHEMBL4780603 | 0.74 | DRD2 (0.38) | DDTKDM4ECNR2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |