Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782258 | 0.81 | KDM4E (0.48) | DPP4TP53KDM4ELMNAALDH1A1 | |
| SCHEMBL14722613 | 0.75 | TGFBR1 (0.48) | GRM5CCR1CCR8 | |
| SCHEMBL4781710 | 0.74 | KDM4E (0.43) | GPR84TP53KDM4ELMNAALDH1A1 | |
| SCHEMBL4600287 | 0.72 | KCNA5 (0.43) | DPP4ALDH1A1ALOX15HTTHSD17B10 | |
| SCHEMBL8893378 | 0.72 | CDC25B (0.36) | HTR2CGRM5TP53KDM4ELMNA | |
| SCHEMBL17456048 | 0.70 | CYP11B1 (0.44) | DPP4KDM4ELMNANPC1RAB9A | |
| SCHEMBL4592340 | 0.69 | KDM4E (0.41) | DPP4KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL2008558 | 0.69 | — | — | |
| SCHEMBL1456807 | 0.68 | GOT1 (0.46) | CASP6HTR2CGRM5HTR2AHTR2B | |
| SCHEMBL30792004 | 0.68 | GOT1 (0.46) | CASP6HTR2CGRM5HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008034579-A1 | 2-HETEROCYCLYL-5-PHENOXYMETHYLPYRIDINE DERIVATIVES AS ANTICANCER AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-03-27 | — | — | WO | disclosed |