Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293533 | 0.78 | KMT2A (0.34) | MAPTPOLBKMT2AALDH1A1HTT | |
| SCHEMBL4782153 | 0.75 | NOTUM (0.37) | MAPTPOLBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4782157 | 0.75 | NOTUM (0.37) | MAPTPOLBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4780603 | 0.69 | DRD2 (0.38) | MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13436194 | 0.68 | CHEK1 (0.40) | — | |
| SCHEMBL14293528 | 0.66 | PKM (0.37) | MAPTPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10076874 | 0.65 | ALDH1A1 (0.56) | MAPTMAPK1KMT2AALDH1A1HTT | |
| SCHEMBL4781747 | 0.65 | NPC1 (0.37) | MAPTATMKMT2AALDH1A1 | |
| SCHEMBL17978569 | 0.62 | HTT (0.46) | MAPTKMT2AHTTSMN1; SMN2SLC5A1 | |
| SCHEMBL31481312 | 0.61 | ALDH1A1 (0.44) | MAPTMAPK1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |