Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348572 | 0.95 | GABRA1 (0.40) | GABRA1GABRB2HMGCRRXRARXRB | |
| SCHEMBL4391448 | 0.86 | TACR1 (0.43) | GABRA1GABRB2HMGCRRXRARXRB | |
| SCHEMBL29727697 | 0.86 | RXRB (0.44) | GABRA1GABRB2HMGCRRXRARXRB | |
| SCHEMBL8826658 | 0.84 | GABRA1 (0.33) | GABRA1GABRB2HMGCRPOLBHTR1D | |
| SCHEMBL5352048 | 0.84 | HMGCR (0.46) | GABRA1GABRB2HMGCRPOLBHTR1D | |
| SCHEMBL13208365 | 0.84 | GABRA1 (0.33) | GABRA1GABRB2HMGCRPOLBHTR1D | |
| SCHEMBL29942298 | 0.84 | HMGCR (0.46) | GABRA1GABRB2HMGCRPOLBHTR1D | |
| SCHEMBL14705813 | 0.82 | ESR1 (0.41) | GABRA1GABRB2RXRARXRBRXRG | |
| SCHEMBL3189726 | 0.81 | GABRA1 (0.35) | GABRA1GABRB2HMGCRRXRARXRB | |
| SCHEMBL3195098 | 0.81 | GABRA1 (0.35) | GABRA1GABRB2HMGCRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486852-A | Fluorine-containing rotaxane molecule and preparation method and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2024-02-02 | — | — | CN | claimed |
| CN-114805152-B | Synthetic method of thioamide | 兰州大学 | 2023-04-14 | — | — | CN | claimed |
| CN-114805152-A | Method for synthesizing thioamide | 兰州大学 | 2022-07-29 | — | — | CN | claimed |
| EP-2145895-B1 | Process for the manufacturing of glycochips | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2013-10-30 | — | — | EP | claimed |
| US-20100035353-A1 | PROCESS FOR THE MANUFACTURING OF GLYCOCHIPS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-02-11 | — | — | US | claimed |
| EP-2145895-A1 | Process for the manufacturing of glycochips | Commissariat à l'Energie Atomique (FR) | 2010-01-20 | — | — | EP | claimed |
| CN-122010944-A | TBC1D 2-targeted aromatic methyl alkenyl matrine derivative and preparation method and application thereof | 广西大学 | 2026-05-12 | — | — | CN | disclosed |
| US-12420270-B2 | Molecular sieve SSZ-116, its synthesis and use | CHEVRON U.S.A. INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-12344533-B2 | Molecular sieve SSZ-116, its synthesis and use | CHEVRON U.S.A. INC. (US) | 2025-07-01 | — | — | US | disclosed |
| EP-4298135-B1 | BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-118994022-A | Preparation method of 1-methyl-4-phenyl ether derivative and application of non-classical antibacterial activity | 中国人民解放军军事科学院军事医学研究院 | 2024-11-22 | — | — | CN | disclosed |
| CN-118851911-A | Dendrimer gel factor based on C-H/pi interaction and application thereof | 常州大学 | 2024-10-29 | — | — | CN | disclosed |
| US-20240158542-A1 | BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-05-16 | — | — | US | disclosed |
| EP-1087005-A1 | Fluorescent diketopyrrolopyrroles | Ciba SC Holding AG (CH) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | disclosed |
| EP-0600952-B1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME (GB) | 1996-04-17 | — | — | EP | disclosed |
| US-5459270-A | Tachykinin antagonist for central nervous systum disorders and cardiovascular disorders | MERCK SHARP & DOHME LIMITED (GB) | 1995-10-17 | — | — | US | disclosed |
| EP-0600952-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | MERCK SHARP & DOHME (GB) | 1994-06-15 | — | — | EP | disclosed |
| WO-1993004040-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME LIMITED (GB) | 1993-03-04 | — | — | WO | disclosed |
| EP-0528495-A1 | Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them | MERCK SHARP & DOHME LTD. (GB) | 1993-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12420270-B2 | Molecular sieve SSZ-116, its synthesis and use | TERT, SIK1, SSU72 | GABRA1 2704/4885GABRB2 3817/4885HMGCR 3528/4885 |
| US-20100035353-A1 | PROCESS FOR THE MANUFACTURING OF GLYCOCHIPS | HGF, HGFAC, HDGF | GABRA1 4405/4885GABRB2 4214/4885HMGCR 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.