Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indoline SCHEMBL7443523 | 0.88 | HSD17B10 (0.58) | HSD17B10ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| Indoline SCHEMBL9124759 | 0.83 | ALOX15 (0.38) | HSD17B10ALOX15 | |
| Benzo[D]Thiazole SCHEMBL28370878 | 0.77 | HSD17B10 (0.50) | HSD17B10ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| Quinoxaline SCHEMBL28175254 | 0.69 | DRD2 (0.40) | HSD17B10ALDH1A1ALOX15 | |
| Benzo[D]Thiazole SCHEMBL29229289 | 0.68 | ALDH1A1 (0.70) | HSD17B10ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| Benzo[D]Thiazole SCHEMBL3324563 | 0.67 | ALDH1A1 (0.76) | HSD17B10ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| Phenazine SCHEMBL28431056 | 0.67 | MAPT (0.44) | HSD17B10ALDH1A1ALOX15 | |
| Benzo[D]Thiazole SCHEMBL230803 | 0.67 | ALDH1A1 (0.54) | HSD17B10ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| Indoline SCHEMBL28757358 | 0.67 | HTR2C (0.48) | HSD17B10ALDH1A1ALOX15 | |
| SCHEMBL60763 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027075-A2 | SULFHYDRYL-REACTIVE, WATER SOLUBLE DYES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-06 | — | — | WO | disclosed |