Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249836 | 0.82 | GRIN2B (0.40) | PTPN1PKM | |
| SCHEMBL4248966 | 0.81 | CHRNB2 (0.38) | CTSD | |
| SCHEMBL4238209 | 0.78 | PKM (0.42) | PKM | |
| SCHEMBL4248188 | 0.77 | ACHE (0.42) | — | |
| SCHEMBL4783288 | 0.75 | SCN1A (0.38) | PTPN1CTSDHRH1SCN1ASCN2A | |
| SCHEMBL4242012 | 0.75 | ACHE (0.45) | — | |
| SCHEMBL4237268 | 0.75 | MEN1 (0.42) | — | |
| SCHEMBL4240892 | 0.74 | SIGMAR1 (0.42) | — | |
| SCHEMBL4237318 | 0.73 | SIGMAR1 (0.44) | — | |
| SCHEMBL4244048 | 0.72 | GRIN2B (0.37) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |