Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783285 | 0.75 | PTPN1 (0.41) | SCN1ASCN2ASCN3APTPN1HRH1 | |
| SCHEMBL5016335 | 0.67 | GABRP (0.49) | PTPN1HRH1 | |
| SCHEMBL5705117 | 0.64 | LMNA (0.48) | PTPN1POLBTSHRSMN1; SMN2 | |
| SCHEMBL5705166 | 0.63 | LMNA (0.42) | POLBTSHRSMN1; SMN2 | |
| SCHEMBL7244805 | 0.63 | SLC18A3 (0.46) | CTSDTSHR | |
| SCHEMBL3165408 | 0.63 | PTPN1 (0.47) | PTPN1HRH1TSHR | |
| SCHEMBL29878136 | 0.63 | PTPN1 (0.47) | PTPN1HRH1TSHR | |
| SCHEMBL4190782 | 0.63 | CHRM3 (0.38) | — | |
| SCHEMBL18986887 | 0.63 | BCHE (0.48) | HTR2CBCHE | |
| SCHEMBL4200496 | 0.62 | CHRM3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |