Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR142 | Q7Z601 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783370 | 0.91 | DDT (0.38) | DDTNPSR1GPR142MIFKDM4E | |
| SCHEMBL4782241 | 0.79 | RAF1 (0.44) | — | |
| SCHEMBL4730805 | 0.78 | DDT (0.42) | DDT | |
| SCHEMBL4778561 | 0.78 | DDT (0.45) | DDTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL4779210 | 0.77 | TEK (0.41) | DDTMIF | |
| SCHEMBL4784000 | 0.76 | DDT (0.34) | DDTMIF | |
| SCHEMBL4781668 | 0.76 | MIF (0.39) | DDTMIF | |
| SCHEMBL14292741 | 0.75 | MIF (0.38) | DDTMIF | |
| SCHEMBL4782901 | 0.75 | BRAF (0.45) | DDT | |
| SCHEMBL4782092 | 0.74 | BRAF (0.34) | DDTNPSR1TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |