Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CD38 | P28907 | 2/20 | 0.33 |
| ▸ | DDT | P30046 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783718 | 0.90 | LMNA (0.36) | LMNACD38DDTCYP3A4ALDH1A1 | |
| SCHEMBL4780945 | 0.84 | DDT (0.33) | LMNADDTALDH1A1MAPTHTT | |
| SCHEMBL4780832 | 0.82 | LMNA (0.42) | LMNACYP3A4ALDH1A1MAPTHTT | |
| SCHEMBL4779770 | 0.82 | NR1H4 (0.39) | LMNADDT | |
| SCHEMBL4778561 | 0.80 | DDT (0.45) | DDTALDH1A1 | |
| SCHEMBL4799766 | 0.79 | DDT (0.32) | DDTMALT1 | |
| SCHEMBL1378336 | 0.78 | LMNA (0.45) | LMNACYP3A4ABL1 | |
| SCHEMBL4778554 | 0.78 | DDT (0.42) | DDT | |
| SCHEMBL4782954 | 0.76 | BRAF (0.40) | — | |
| SCHEMBL4781726 | 0.75 | MAPK14 (0.41) | LMNADDTCYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |