Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 9/20 | 0.38 |
| ▸ | DDT | P30046 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13843780 | 0.89 | NR1I2 (0.41) | NR1H4NR1I2DDT | |
| SCHEMBL4779766 | 0.89 | NR1I2 (0.41) | NR1I2TSHR | |
| SCHEMBL4784135 | 0.84 | CYP1A2 (0.48) | NR1I2POLBTSHR | |
| SCHEMBL4780945 | 0.83 | DDT (0.33) | NR1I2DDTLMNAPOLB | |
| SCHEMBL4778561 | 0.83 | DDT (0.45) | NR1I2DDT | |
| SCHEMBL4783723 | 0.82 | LMNA (0.35) | DDTLMNA | |
| SCHEMBL4778554 | 0.81 | DDT (0.42) | NR1I2DDT | |
| SCHEMBL4013585 | 0.80 | BRAF (0.40) | DDT | |
| SCHEMBL4779210 | 0.77 | TEK (0.41) | NR1I2DDT | |
| SCHEMBL4799766 | 0.77 | DDT (0.32) | NR1I2DDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |