Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786223 | 0.89 | MAOB (0.46) | ALDH1A1SLC9A1ADORA2AADORA1PIN1 | |
| SCHEMBL4787618 | 0.88 | CYP1A2 (0.47) | GAASMN1; SMN2ALDH1A1DHODHADORA2A | |
| SCHEMBL4787412 | 0.81 | TP53 (0.49) | GAAALDH1A1PKM | |
| SCHEMBL4784404 | 0.77 | SLC9A1 (0.51) | TLR8SLC9A1 | |
| SCHEMBL4788478 | 0.77 | HSD11B1 (0.42) | RAB9ASMN1; SMN2ALDH1A1ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL8699835 | 0.73 | DHODH (0.50) | RAB9ASMN1; SMN2ALDH1A1DHODHHDAC2 | |
| SCHEMBL4786802 | 0.72 | ALDH1A1 (0.47) | GAAALDH1A1 | |
| SCHEMBL4787790 | 0.71 | SLC9A1 (0.54) | RAB9ASLC9A1PIN1 | |
| SCHEMBL2682845 | 0.69 | CYP1A2 (0.55) | RAB9AALDH1A1PKMDHODHADORA2A | |
| SCHEMBL4936806 | 0.69 | SLC9A1 (0.61) | GAAALDH1A1SLC9A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008111794-A1 | 4-METHYLIMIDAZOL-5-YLCARBONYLGUANIDINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE ISCHEMIC HEART DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-09-18 | — | — | WO | disclosed |