Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.40 |
| ▸ | WNT3A | P56704 | 3/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785756 | 0.91 | CTNNB1 (0.49) | CES2CES1MAOBCTNNB1WNT3A | |
| SCHEMBL5503013 | 0.76 | CTNNB1 (0.49) | CTNNB1WNT3ASMYD3NPC1RAB9A | |
| SCHEMBL4734952 | 0.74 | MAOB (0.40) | CES2CES1MAOBPGR | |
| SCHEMBL5753071 | 0.74 | ALDH1A1 (0.52) | CTNNB1WNT3ASMYD3RAB9AKIF11 | |
| SCHEMBL2647988 | 0.73 | CTNNB1 (0.55) | CTNNB1WNT3ASMYD3 | |
| SCHEMBL31085181 | 0.73 | KDM4E (0.49) | CTNNB1WNT3ASMYD3NPC1RAB9A | |
| SCHEMBL4784600 | 0.73 | IDO1 (0.57) | CES2CES1IDO1TDO2RAB9A | |
| SCHEMBL1907961 | 0.73 | KDM4E (0.49) | CTNNB1WNT3ASMYD3NPC1RAB9A | |
| SCHEMBL15104920 | 0.73 | TSHR (0.53) | CTNNB1WNT3ASMYD3NPC1RAB9A | |
| SCHEMBL13263896 | 0.73 | CES2 (0.53) | CES2CES1MAOBIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076044-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |