Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781080 | 0.86 | MEN1 (0.35) | MEN1KMT2ACCR8 | |
| SCHEMBL4732673 | 0.77 | CNR2 (0.40) | NAMPTGBA1CNR2PKMCCR8 | |
| SCHEMBL4784263 | 0.74 | MEN1 (0.47) | MEN1KMT2APKMALDH1A1 | |
| SCHEMBL4733897 | 0.73 | CNR2 (0.40) | NAMPTGBA1CNR2PKMCCR8 | |
| SCHEMBL4733838 | 0.67 | PSMD14 (0.43) | MEN1KMT2ACNR2PKMALDH1A1 | |
| SCHEMBL4732817 | 0.66 | CNR2 (0.39) | MEN1KMT2AGBA1CNR2PKM | |
| SCHEMBL4733963 | 0.65 | CNR2 (0.38) | MEN1KMT2AGBA1CNR2PKM | |
| SCHEMBL4730155 | 0.64 | CNR2 (0.39) | GBA1CNR2PKMCNR1 | |
| SCHEMBL4733373 | 0.64 | BRD4 (0.40) | MEN1KMT2ANAMPTCNR2PKM | |
| SCHEMBL4732243 | 0.64 | CNR2 (0.39) | GBA1CNR2PKMALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |