Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784054 | 0.90 | PIK3CA (0.37) | ROCK1TSHRSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL4857757 | 0.87 | DRD2 (0.44) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4785161 | 0.87 | CSNK1E (0.36) | PIK3CBPDE4BPDE4D | |
| SCHEMBL4784447 | 0.85 | IDH1 (0.37) | ALDH1A1TP53PDE4BPDE4D | |
| SCHEMBL4785292 | 0.84 | ROCK1 (0.35) | ROCK1TSHRSMN1; SMN2MAPK1PAK4 | |
| SCHEMBL4784674 | 0.77 | HRH4 (0.43) | SMN1; SMN2CYP1A2ALDH1A1TP53 | |
| SCHEMBL4782277 | 0.74 | ADORA2A (0.35) | MAPK1ALDH1A1 | |
| SCHEMBL4782616 | 0.74 | IDH1 (0.40) | — | |
| SCHEMBL4782447 | 0.73 | HRH4 (0.36) | TSHRSMN1; SMN2ALDH1A1TP53PDE4B | |
| SCHEMBL4784083 | 0.73 | PIK3CA (0.41) | CYP1A2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |