Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367573 | 0.68 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL7399363 | 0.58 | KDM4E (0.30) | — | |
| SCHEMBL28948825 | 0.57 | TDO2 (0.39) | ALDH1A1CCNE1CDK2CYP19A1JAK2 | |
| SCHEMBL2355698 | 0.57 | CEL (0.37) | ALDH1A1CCNE1CDK2CCNT1CDK1 | |
| SCHEMBL30397973 | 0.57 | MAP4K4 (0.41) | ALDH1A1SMN1; SMN2CCNE1CDK2 | |
| SCHEMBL9600106 | 0.57 | TDO2 (0.35) | CCNE1CDK2CCNT1CDK1CDK4 | |
| SCHEMBL3101449 | 0.56 | TDO2 (0.38) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL9350412 | 0.56 | TDO2 (0.38) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL15243172 | 0.56 | TDO2 (0.43) | JAK2JAK1TYK2JAK3TDO2 | |
| Benzene SCHEMBL27853973 | 0.55 | PTGDR2 (0.52) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069500-A1 | TRIAZOLOPYRIDAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | disclosed |