Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786193 | 0.95 | EPHX2 (0.56) | POLBMCHR1MEN1KMT2AMCHR2 | |
| SCHEMBL4786204 | 0.92 | EPHX2 (0.60) | MCHR1MCHR2EPHX2HTR7MAPT | |
| SCHEMBL4786227 | 0.91 | EPHX2 (0.59) | MCHR1MCHR2EPHX2MAPT | |
| SCHEMBL4786966 | 0.88 | EPHX2 (0.59) | MCHR1MCHR2EPHX2HTR7HTR3A | |
| SCHEMBL4788178 | 0.87 | EPHX2 (0.58) | MCHR1MCHR2EPHX2HTR3A | |
| SCHEMBL4788021 | 0.85 | EPHX2 (0.64) | MCHR1MCHR2EPHX2HTR7MAPT | |
| SCHEMBL4787450 | 0.84 | EPHX2 (0.63) | POLBMCHR1MEN1KMT2AMCHR2 | |
| SCHEMBL4788976 | 0.83 | POLB (0.54) | POLBMCHR1MEN1KMT2AMCHR2 | |
| SCHEMBL4787642 | 0.82 | EPHX2 (0.63) | MCHR1EPHX2HTR3A | |
| SCHEMBL4788497 | 0.80 | HTR3A (0.55) | POLBMCHR1MEN1KMT2AMCHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |