Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.39 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667635 | 0.86 | KMT2A (0.40) | DPP7ALDH1A1SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL3808885 | 0.85 | DPP7 (0.41) | DPP7ALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL3670283 | 0.84 | SIGMAR1 (0.39) | DPP7ALDH1A1SIGMAR1 | |
| SCHEMBL4736472 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SIGMAR1TSHR | |
| SCHEMBL4731396 | 0.80 | KCNH2 (0.40) | RORCALDH1A1CYP3A4MAPK1 | |
| SCHEMBL4738420 | 0.78 | ALDH1A1 (0.39) | ALDH1A1SIGMAR1CYP3A4CYP2D6UBE2M | |
| SCHEMBL3727160 | 0.73 | RORC (0.38) | RORCALDH1A1 | |
| SCHEMBL4734750 | 0.73 | DPP7 (0.37) | DPP7ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL4786490 | 0.71 | TNKS (0.42) | ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL3663968 | 0.69 | NSD2 (0.34) | RORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |