Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724470 | 0.86 | HTR2A (0.37) | RORCCCR5KCNH2HTR2AHTR2C | |
| SCHEMBL4783965 | 0.78 | CHRM2 (0.44) | — | |
| SCHEMBL3663968 | 0.77 | NSD2 (0.34) | RORCALDH1A1NSD2 | |
| SCHEMBL3722537 | 0.76 | OPRM1 (0.39) | HTR2AHTR2CAGTR2 | |
| SCHEMBL3723935 | 0.75 | MCL1 (0.39) | ALDH1A1KCNH2HTR2AHTR2C | |
| SCHEMBL3728078 | 0.74 | HTR7 (0.37) | ALDH1A1HTR2AHTR2CNPSR1 | |
| SCHEMBL4786234 | 0.73 | DPP7 (0.39) | RORCALDH1A1 | |
| SCHEMBL4731396 | 0.73 | KCNH2 (0.40) | RORCALDH1A1KCNH2 | |
| SCHEMBL3724780 | 0.73 | TAS2R14 (0.44) | HTR2AHTR2CNPSR1 | |
| SCHEMBL4738420 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |