Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787514 | 0.88 | L3MBTL1 (0.52) | L3MBTL1TSHRALDH1A1ALOX15GFER | |
| SCHEMBL5244145 | 0.86 | L3MBTL1 (0.50) | L3MBTL1TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL4745401 | 0.85 | TSHR (0.47) | L3MBTL1TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL5242720 | 0.83 | ALDH1A1 (0.67) | L3MBTL1TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL4784036 | 0.83 | TSHR (0.67) | L3MBTL1TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL4785121 | 0.82 | TSHR (0.54) | L3MBTL1TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL4788589 | 0.82 | PKLR (0.45) | L3MBTL1ALDH1A1MAPK1MAPT | |
| SCHEMBL4788394 | 0.82 | CHRM1 (0.48) | L3MBTL1ALDH1A1MAPTSMN1; SMN2HTR6 | |
| SCHEMBL4787536 | 0.81 | ALDH1A1 (0.55) | L3MBTL1TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL5242949 | 0.81 | ALDH1A1 (0.53) | L3MBTL1TSHRALDH1A1MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |