Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242720 | 0.92 | ALDH1A1 (0.67) | ALDH1A1GAAMAPTALOX15SMN1; SMN2 | |
| SCHEMBL4745401 | 0.86 | TSHR (0.47) | ALDH1A1GAAMAPTALOX15SMN1; SMN2 | |
| SCHEMBL5244145 | 0.85 | L3MBTL1 (0.50) | ALDH1A1GAAALOX15TSHRMAPK1 | |
| SCHEMBL4787514 | 0.85 | L3MBTL1 (0.52) | ALDH1A1GAAALOX15HTTTSHR | |
| SCHEMBL4786573 | 0.84 | CCR1 (0.43) | ALDH1A1GAAMAPTALOX15SMN1; SMN2 | |
| SCHEMBL5242949 | 0.83 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTALOX15SMN1; SMN2 | |
| SCHEMBL8154008 | 0.82 | MAPT (0.49) | ALDH1A1MAPTALOX15TSHRMEN1 | |
| SCHEMBL5244384 | 0.81 | HSD11B1 (0.49) | ALDH1A1GAAALOX15L3MBTL1KDM4E | |
| SCHEMBL4786255 | 0.81 | L3MBTL1 (0.48) | ALDH1A1MAPTALOX15SMN1; SMN2TSHR | |
| SCHEMBL5245687 | 0.81 | HSD11B1 (0.52) | ALDH1A1GAAMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |