Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.82 |
| ▸ | HTT | P42858 | 1/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743525 | 0.82 | CA1 (0.56) | ALDH1A1HTTNPSR1CA1CA2 | |
| SCHEMBL4745925 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HTTNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL4748024 | 0.81 | CA1 (0.67) | ALDH1A1HTTNPSR1CA1CA2 | |
| SCHEMBL4747947 | 0.80 | GFER (0.72) | ALDH1A1SMN1; SMN2HSD17B10CA1CA2 | |
| SCHEMBL4747309 | 0.80 | HTR7 (0.72) | CA1CA2CA9GFERKMT2A | |
| SCHEMBL4747357 | 0.80 | PTGS2 (0.61) | ALDH1A1CA1CA2CA9GFER | |
| SCHEMBL4745920 | 0.80 | CA1 (0.60) | ALDH1A1HTTNPSR1CA1CA2 | |
| SCHEMBL4747367 | 0.80 | TUBB4A (0.62) | ALDH1A1HTTNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL4743532 | 0.79 | GFER (0.70) | ALDH1A1HTTNPSR1CA1CA2 | |
| SCHEMBL4747965 | 0.79 | KMT2A (0.56) | ALDH1A1HTTNPSR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |