Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 8/20 | 0.48 |
| ▸ | FABP1 | P07148 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786465 | 0.92 | PKLR (0.47) | PKLRFABP1L3MBTL1HTR2AHTR2C | |
| SCHEMBL4788589 | 0.91 | PKLR (0.45) | PKLRFABP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL4786322 | 0.90 | PKLR (0.45) | PKLRFABP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL4786573 | 0.87 | CCR1 (0.43) | L3MBTL1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4787288 | 0.86 | PKLR (0.48) | PKLRFABP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL4786353 | 0.85 | ALDH1A1 (0.49) | PKLRL3MBTL1ALDH1A1GAAMEN1 | |
| SCHEMBL8155705 | 0.85 | L3MBTL1 (0.41) | FABP1L3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL4788077 | 0.83 | PKLR (0.47) | PKLRL3MBTL1ALDH1A1GAA | |
| SCHEMBL8152556 | 0.83 | L3MBTL1 (0.39) | FABP1L3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL8152661 | 0.81 | L3MBTL1 (0.41) | FABP1L3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |