Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 15/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787288 | 0.91 | PKLR (0.48) | PKLRL3MBTL1ALDH1A1GAA | |
| SCHEMBL4788589 | 0.89 | PKLR (0.45) | PKLRL3MBTL1ALDH1A1GAA | |
| SCHEMBL4786573 | 0.88 | CCR1 (0.43) | L3MBTL1ALDH1A1GAA | |
| SCHEMBL4786322 | 0.87 | PKLR (0.45) | PKLRL3MBTL1ALDH1A1GAA | |
| SCHEMBL8150778 | 0.86 | L3MBTL1 (0.41) | PKLRL3MBTL1ALDH1A1GAA | |
| SCHEMBL4786465 | 0.85 | PKLR (0.47) | PKLRL3MBTL1ALDH1A1GAA | |
| SCHEMBL4787598 | 0.83 | PKLR (0.48) | PKLRL3MBTL1ALDH1A1GAA | |
| SCHEMBL4786353 | 0.83 | ALDH1A1 (0.49) | PKLRL3MBTL1ALDH1A1GAA | |
| SCHEMBL8152661 | 0.83 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1GAA | |
| SCHEMBL8155705 | 0.83 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |