SCHEMBL4467633

SCHEMBL4467633

O=C1OCCc2cc(C3CCCCC3)nc(Cl)c21

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PSD A5PKW4 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PGR P06401 2/20 0.32
SRC P12931 1/20 0.31
TLR8 Q9NR97 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
CEL P19835 1/20 0.31
CYP1B1 Q16678 1/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
LMNA P02545 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4470420 0.84 HRH4 (0.36) L3MBTL1PGRPDE4APDE4BPDE4C
SCHEMBL4483308 0.84 L3MBTL1 (0.34) L3MBTL1PGRTLR8PDE4APDE4B
SCHEMBL4248613 0.80 KDM4E (0.43) L3MBTL1PDE4APDE4BPDE4CPDE4D
SCHEMBL4788972 0.77 PGR (0.46) PSDPGR
SCHEMBL4067369 0.76 MAOA (0.35) PGR
SCHEMBL4245491 0.74 PGR (0.35) L3MBTL1PGRSMN1; SMN2RAB9A
SCHEMBL4065469 0.74 ALDH1A1 (0.43) L3MBTL1PGRSMN1; SMN2LMNA
SCHEMBL4067298 0.72 ALDH1A1 (0.41) L3MBTL1PDE4BSMN1; SMN2LMNA
SCHEMBL4071256 0.72 MAPT (0.36) L3MBTL1NPC1RAB9ALMNA
SCHEMBL4063663 0.70 MAOA (0.31) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7601736-B2 Such as 3,4-dihydro-pyrano[3,4-c]pyridine-1-on; cytokine suppressive antiinflammatory drugs; analgesics SK CHEMICALS CO., LTD. (KR) 2009-10-13 US claimed
US-20070254909-A1 Novel Pyridine Derivatives, a Process for Their Preparation and a Pharmaceutical Composition Containing the Same SK CHEMICALS CO., LTD. (KR) 2007-11-01 US claimed
US-7601736-B2 Such as 3,4-dihydro-pyrano[3,4-c]pyridine-1-on; cytokine suppressive antiinflammatory drugs; analgesics SK CHEMICALS CO., LTD. (KR) 2009-10-13 US disclosed
US-20070254909-A1 Novel Pyridine Derivatives, a Process for Their Preparation and a Pharmaceutical Composition Containing the Same SK CHEMICALS CO., LTD. (KR) 2007-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254909-A1 Novel Pyridine Derivatives, a Process for Their Preparation and a Pharmaceutical Composition Containing the Same IL5, IL1B, P2RY4 PSD 2370/4885L3MBTL1 4883/4885PGR 1009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.