Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754290 | 0.86 | HTR1A (0.50) | HTR7ABCB1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4863289 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2DRD2HTR2A | |
| SCHEMBL4789257 | 0.84 | SMN1; SMN2 (0.49) | ABCB1ALDH1A1LMNASMN1; SMN2ENPP2 | |
| SCHEMBL4908879 | 0.80 | HTR7 (0.50) | HTR7ABCB1DRD2HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL4788931 | 0.73 | GAA (0.53) | HTR7ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL4753368 | 0.71 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4751070 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4751068 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2HTR2AMEN1 | |
| SCHEMBL4752802 | 0.71 | ALDH1A1 (0.41) | HTR7ABCB1ALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL4750825 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |