Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888793 | 0.70 | HTR6 (0.41) | ALDH1A1KMT2AHTTC5AR1HTR6 | |
| SCHEMBL31689520 | 0.70 | CRY1 (0.49) | MAPTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL12330758 | 0.70 | CRY1 (0.49) | MAPTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL5966749 | 0.70 | KMT2A (0.36) | MAPTALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL5317921 | 0.70 | GAA (0.41) | GAAALDH1A1KMT2AHPGDPER2 | |
| SCHEMBL6285846 | 0.69 | MAPT (1.00) | MAPTKDM4EGAAALDH1A1MCL1 | |
| SCHEMBL28279 | 0.69 | MAPT (1.00) | MAPTKDM4EGAAALDH1A1MCL1 | |
| SCHEMBL29363940 | 0.69 | MAPT (1.00) | MAPTKDM4EGAAALDH1A1MCL1 | |
| SCHEMBL1509330 | 0.68 | KDM4E (0.56) | MAPTKDM4EGAAALDH1A1CES2 | |
| SCHEMBL29851883 | 0.68 | KDM4E (0.56) | MAPTKDM4EGAAALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928887-A1 | METHODS OF PREPARING QUINOLONE ANALOGS | Cylene Pharmaceuticals, Inc. (US) | 2008-06-11 | — | — | EP | claimed |
| WO-2007019295-A1 | METHODS OF PREPARING QUINOLONE ANALOGS | CYLENE PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | claimed |