Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789823 | 0.85 | HSD11B1 (0.47) | KMT2AL3MBTL1KDM4ELMNAHSD17B10 | |
| SCHEMBL5020141 | 0.80 | GPR119 (0.41) | GPR119KMT2AL3MBTL1PANK3PPARG | |
| SCHEMBL2155271 | 0.71 | GPR119 (0.59) | GPR119KMT2AL3MBTL1PANK3CNR2 | |
| SCHEMBL4754484 | 0.70 | GPR119 (0.54) | GPR119KMT2AL3MBTL1PANK3CNR2 | |
| SCHEMBL4674581 | 0.69 | CNR2 (0.49) | GPR119KMT2AL3MBTL1PANK3CNR2 | |
| SCHEMBL5020140 | 0.68 | GRIN2D (0.36) | GPR119KMT2AL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL26758698 | 0.68 | KMT2A (0.45) | GPR119KMT2APANK3CNR2KDM4E | |
| SCHEMBL4789741 | 0.67 | DRD2 (0.43) | GPR119KMT2AL3MBTL1PANK3CNR2 | |
| SCHEMBL30567093 | 0.67 | GPR119 (0.39) | GPR119KMT2AL3MBTL1PANK3PPARG | |
| SCHEMBL22581675 | 0.67 | GPR119 (0.39) | GPR119KMT2AL3MBTL1PANK3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | claimed |
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | disclosed |