Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248113 | 0.89 | ALDH1A1 (0.65) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL4789964 | 0.82 | CA2 (0.53) | L3MBTL1MAPK1ALDH1A1TDP1MEN1 | |
| SCHEMBL29046265 | 0.82 | ALDH1A1 (0.49) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL1318640 | 0.82 | L3MBTL1 (0.57) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL27139938 | 0.82 | TSHR (0.58) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL27738415 | 0.81 | MAPK1 (0.61) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL9370013 | 0.81 | TDP1 (0.61) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL25187337 | 0.80 | ALDH1A1 (0.55) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL27467299 | 0.80 | ALDH1A1 (0.55) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL4641557 | 0.80 | AKR1B1 (0.56) | L3MBTL1MAPK1ALDH1A1PAMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024243289-A2 | GUT MICROBE DERIVED AROMATIC AMINO ACID METABOLITES FOR DETECTION AND TREATMENT OF DISEASE | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-11-28 | — | — | WO | claimed |
| CN-118225947-B | Method for detecting nonsteroidal impurity components in natural source conjugated estrogens | 新疆特丰药业股份有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-118225947-A | Method for detecting nonsteroidal impurity components in natural source conjugated estrogens | 新疆特丰药业股份有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-110068618-B | Detection method of intestinal flora metabolites related to nephropathy | 中国科学院大连化学物理研究所 | 2022-02-01 | — | — | CN | claimed |
| CN-112689755-A | Mass spectrometry for detecting and quantifying microflora-related metabolites | 梅塔博隆股份有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-109298115-A | A variety of metabolin quantitative detecting methods and metabolism chip in biological sample | 深圳市绘云生物科技有限公司 | 2019-02-01 | — | — | CN | claimed |
| JP-2012500391-A | — | — | 2012-01-05 | — | — | JP | claimed |
| EP-2331955-A1 | A METHOD OF DIAGNOSING A RESPIRATORY DISEASE | The Governors of the University of Alberta (CA) | 2011-06-15 | — | — | EP | claimed |
| WO-2010020058-A1 | A METHOD OF DIAGNOSING A RESPIRATORY DISEASE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-02-25 | — | — | WO | claimed |
| WO-2024243289-A2 | GUT MICROBE DERIVED AROMATIC AMINO ACID METABOLITES FOR DETECTION AND TREATMENT OF DISEASE | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-11-28 | — | — | WO | disclosed |
| CN-118225947-B | Method for detecting nonsteroidal impurity components in natural source conjugated estrogens | 新疆特丰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118225947-B | Method for detecting nonsteroidal impurity components in natural source conjugated estrogens | 新疆特丰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118225947-A | Method for detecting nonsteroidal impurity components in natural source conjugated estrogens | 新疆特丰药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118225947-A | Method for detecting nonsteroidal impurity components in natural source conjugated estrogens | 新疆特丰药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-2331955-A1 | A METHOD OF DIAGNOSING A RESPIRATORY DISEASE | The Governors of the University of Alberta (CA) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025303-A9 | DOSING AND MONITORING PATIENTS ON NITROGEN-SCAVENGING DRUGS | HYPERION THERAPEUTICS (US) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010025303-A1 | DOSING AND MONITORING PATIENTS ON NITROGEN-SCAVENGING DRUGS | HYPERION THERAPEUTICS (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010020058-A1 | A METHOD OF DIAGNOSING A RESPIRATORY DISEASE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-02-25 | — | — | WO | disclosed |
| US-20100008859-A1 | METHODS OF TREATMENT USING AMMONIA-SCAVENGING DRUGS | HORIZON THERAPEUTICS U.S. HOLDING LLC | 2010-01-14 | — | — | US | disclosed |
| WO-2009134460-A1 | METHODS OF TREATMENT USING AMMONIA-SCAVENGING DRUGS | HYPERION THERAPEUTICS (US) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100008859-A1 | METHODS OF TREATMENT USING AMMONIA-SCAVENGING DRUGS | OAT, SLC1A5, GLS | L3MBTL1 2878/4885MAPK1 3981/4885ALDH1A1 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.