SCHEMBL4789965

SCHEMBL4789965

CCOc1c(F)cc(F)c(I)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
TUBB1 Q9H4B7 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
THRB P10828 1/20 0.31
BPTF Q12830 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841907 0.79 ILK (0.33)
SCHEMBL31015975 0.79 ILK (0.33)
SCHEMBL3835882 0.76 LMNA (0.37) TUBB1ALDH1A1LMNAHTTHTR2A
SCHEMBL22114300 0.70 GRIN2D (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3841470 0.69 LMNA (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3843002 0.69 PTGS2 (0.35) ALDH1A1
SCHEMBL25028970 0.69 ALDH1A1 (0.34) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14524684 0.69 HTR2A (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4753814 0.69 ALDH1A1 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12129089 0.68 L3MBTL1 (0.33) TUBB1ALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1973881-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES Dow Agrosciences LLC (US) 2008-10-01 EP disclosed
WO-2007082098-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2007-07-19 WO disclosed