Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790366 | 0.83 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1TDP1KMT2A | |
| SCHEMBL13730470 | 0.71 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1TDP1KMT2A | |
| SCHEMBL7334283 | 0.68 | ALDH1A1 (0.62) | NPC1RAB9AALDH1A1TDP1KMT2A | |
| SCHEMBL7343483 | 0.67 | ALDH1A1 (0.61) | NPC1RAB9AALDH1A1TDP1KMT2A | |
| SCHEMBL3718482 | 0.63 | NPSR1 (0.44) | NPC1RAB9AALDH1A1TDP1KMT2A | |
| SCHEMBL4592999 | 0.63 | P2RX7 (0.40) | ALDH1A1TDP1KMT2AMEN1NPSR1 | |
| SCHEMBL6394938 | 0.63 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1TDP1KMT2A | |
| SCHEMBL30378846 | 0.62 | HSD17B10 (0.60) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL9828569 | 0.62 | HSD17B10 (0.60) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| 3-Formylindole SCHEMBL29082887 | 0.62 | CYP2A6 (0.77) | NPC1RAB9AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157740-A2 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |