Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337859 | 0.88 | L3MBTL1 (0.38) | P2RX3L3MBTL1KDM4EEGLN1EGLN2 | |
| SCHEMBL5340240 | 0.87 | RXRA (0.38) | L3MBTL1KDM4EEGLN1EGLN2RXRA | |
| SCHEMBL5341336 | 0.72 | XDH (0.36) | EGLN1EGLN2RXRANR4A2ALDH1A1 | |
| SCHEMBL4794080 | 0.69 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL842220 | 0.67 | MAPT (0.37) | KDM4EALDH1A1MAPT | |
| SCHEMBL1232835 | 0.67 | ALDH1A1 (0.36) | L3MBTL1EGLN1EGLN2ALDH1A1MAPT | |
| SCHEMBL1232939 | 0.65 | TOP2A (0.37) | L3MBTL1KDM4EEGLN2ALDH1A1 | |
| SCHEMBL28753431 | 0.65 | TOP2A (0.37) | L3MBTL1EGLN2ALDH1A1 | |
| SCHEMBL5340227 | 0.65 | KDM4E (0.42) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL4793644 | 0.64 | ALDH1A1 (0.35) | P2RX3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |