Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794237 | 0.79 | MEN1 (0.38) | KDM4EALDH1A1HPGDHSD17B10HSD11B1 | |
| SCHEMBL8828607 | 0.71 | ADRA1A (0.48) | — | |
| SCHEMBL8828730 | 0.71 | DRD2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL8828650 | 0.71 | DRD2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL8828673 | 0.71 | ADRA1A (0.48) | — | |
| Hydrochloric Acid SCHEMBL8828819 | 0.70 | DRD2 (0.42) | ACACB | |
| Hydrochloric Acid SCHEMBL8828589 | 0.70 | ACACB (0.41) | ACACB | |
| Hydrochloric Acid SCHEMBL8828481 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1 | |
| SCHEMBL8828467 | 0.69 | — | — | |
| SCHEMBL4794245 | 0.69 | ALDH1A1 (0.45) | ACACBKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |