SCHEMBL29467342

SCHEMBL29467342

CCCCC(N)(C(=O)O)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HLCS P50747 6/20 0.64
TDP1 Q9NUW8 6/20 0.63
MEN1 O00255 1/20 0.63
ABL1 P00519 1/20 0.63
LMNA P02545 1/20 0.63
PKM P14618 1/20 0.63
IDE P14735 1/20 0.63
MAPK1 P28482 1/20 0.63
KMT2A Q03164 1/20 0.63
RIN1 Q13671 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
CA12 O43570 7/20 0.48
CA1 P00915 7/20 0.48
CA2 P00918 7/20 0.48
CA9 Q16790 7/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31028942 1.00 HLCS (0.64) HLCSTDP1MEN1ABL1LMNA
SCHEMBL479444 0.85 HLCS (0.72) HLCSTDP1MEN1ABL1LMNA
Hydrochloric Acid SCHEMBL7374429 0.84 HLCS (0.70) HLCSTDP1MEN1ABL1LMNA
Biotin SCHEMBL6033491 0.83 TDP1 (0.87) HLCSTDP1MEN1ABL1LMNA
Biotin SCHEMBL8651197 0.83 TDP1 (0.87) HLCSTDP1MEN1ABL1LMNA
Biotin SCHEMBL3518095 0.83 TDP1 (0.87) HLCSTDP1MEN1ABL1LMNA
Biotin SCHEMBL27671459 0.83 TDP1 (0.87) HLCSTDP1MEN1ABL1LMNA
SCHEMBL5992825 0.82 HLCS (0.59) HLCSTDP1MEN1ABL1LMNA
Biotin SCHEMBL8672968 0.82 TDP1 (0.85) HLCSTDP1MEN1ABL1LMNA
SCHEMBL20411845 0.81 HLCS (0.77) HLCSTDP1MEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584172-B2 Chromosome biomarker Oxford BioDynamics PLC (GB) 2026-03-24 US disclosed
WO-2026047046-A1 SCREENING METHOD USING CHROMOSOMAL CONFORMATIONS FOR DETECTING COLORECTAL CANCER Oxford BioDynamics PLC (GB) 2026-03-05 WO disclosed
US-20260002208-A1 CHROMOSOME INTERACTIONS Oxford BioDynamics PLC (GB) 2026-01-01 US disclosed
US-20260002942-A1 ANTI-DRUG ANTIBODY ASSAY HOFFMANN LA ROCHE (US) 2026-01-01 US disclosed
WO-2025215190-A1 METHOD OF TYPING CHROMOSOME MARKERS Oxford BioDynamics PLC (GB) 2025-10-16 WO disclosed
WO-2025215189-A1 CHROMOSOME MARKER TEST Oxford BioDynamics PLC (GB) 2025-10-16 WO disclosed
US-12378315-B2 Anti-rabbit CD19 antibodies and methods of use HOFFMANN-LA ROCHE INC. (US) 2025-08-05 US disclosed
EP-4301874-B1 CHROMOSOME INTERACTION MARKERS Oxford BioDynamics PLC (GB) 2025-04-23 EP disclosed
WO-2025062136-A1 CHROMOSOME DETECTION ASSAY Oxford BioDynamics PLC (GB) 2025-03-27 WO disclosed
EP-4463567-A1 METHODS AND COMPOSITIONS FOR TRANSCRIPTOME ANALYSIS JumpCode Genomics, Inc. (US) 2024-11-20 EP disclosed
US-20220333199-A1 Diagnostic Chromosome Marker Oxford BioDynamics PLC (GB) 2022-10-20 US disclosed
WO-2022185062-A1 CHROMOSOME INTERACTION MARKERS Oxford BioDynamics PLC (GB) 2022-09-09 WO disclosed
US-20220282328-A1 Chromosome Biomarker Oxford BioDynamics PLC (GB) 2022-09-08 US disclosed
US-11434522-B1 Detection of chromosome interactions Oxford BioDynamics PLC (GB) 2022-09-06 US disclosed
EP-4028547-A1 DIAGNOSTIC CHROMOSOME MARKER Oxford BioDynamics PLC (GB) 2022-07-20 EP disclosed
WO-2022148957-A1 CHROMOSOME INTERACTIONS Oxford BioDynamics PLC (GB) 2022-07-14 WO disclosed
WO-2022148958-A1 ANALYSIS METHOD Oxford BioDynamics PLC (GB) 2022-07-14 WO disclosed
US-20220135672-A1 ANTI-RABBIT CD19 ANTIBODIES AND METHODS OF USE HOFFMANN-LA ROCHE INC. (US) 2022-05-05 US disclosed
WO-2022079418-A1 DISEASE MARKER Oxford BioDynamics PLC (GB) 2022-04-21 WO disclosed
EP-3966350-A1 CHROMOSOME CONFORMATION MARKERS OF PROSTATE CANCER AND LYMPHOMA Oxford BioDynamics PLC (GB) 2022-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260002208-A1 CHROMOSOME INTERACTIONS MED25, RBM25, TERF2IP HLCS 3430/4885TDP1 152/4885MEN1 2048/4885
US-12584172-B2 Chromosome biomarker SMCHD1, SMC4, SMC3 HLCS 3605/4885TDP1 33/4885MEN1 3761/4885
US-20260002942-A1 ANTI-DRUG ANTIBODY ASSAY SHBG, CD2, CA13 HLCS 249/4885TDP1 3440/4885MEN1 4616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.