Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.50 |
| ▸ | CTSK | P43235 | 14/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795003 | 1.00 | CTSS (0.50) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL5115667 | 0.87 | CTSS (0.57) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL1722314 | 0.87 | CTSS (0.57) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL22109892 | 0.86 | CTSK (0.50) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL25319652 | 0.84 | CTSS (0.48) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL25319648 | 0.84 | CTSS (0.48) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL12602587 | 0.84 | CTSK (0.59) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL9697740 | 0.84 | CTSS (0.52) | CTSSCTSKCTSLCTSB | |
| SCHEMBL16839646 | 0.84 | SYK (0.48) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL31086524 | 0.84 | CYP2D6 (0.50) | CTSSCTSKCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083279-A | Oxazepine compounds and their use in the treatment of cancer | 基因泰克公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-110678469-B | Substituted pyrimidinium compounds and derivatives for combating animal pests | 巴斯夫欧洲公司 | 2023-03-03 | — | — | CN | disclosed |
| US-11542280-B2 | Substituted pyrimidinium compounds and derivatives for combating animal pests | BASF SE (DE) | 2023-01-03 | — | — | US | disclosed |
| US-20200131198-A1 | Substituted pyrimidinium compounds and derivatives for combating animal pests | BASF SE (DE) | 2020-04-30 | — | — | US | disclosed |
| EP-3642203-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2020-04-29 | — | — | EP | disclosed |
| CN-110678469-A | Substituted pyrimidinium compounds and derivatives for combating animal pests | 巴斯夫欧洲公司 | 2020-01-10 | — | — | CN | disclosed |
| WO-2018234202-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2018-12-27 | — | — | WO | disclosed |
| US-20080242671-A1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2008-10-02 | — | — | US | disclosed |
| US-7384970-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2008-06-10 | — | — | US | disclosed |
| US-20040248887-A1 | Inhibitors of cathepsin S | IRM LLC (BM) | 2004-12-09 | — | — | US | disclosed |
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248887-A1 | Inhibitors of cathepsin S | CTSS, CTSB, CTSZ | CTSS 1/4885CTSK 9/4885CTSL 11/4885 |
| US-20080242671-A1 | INHIBITORS OF CATHEPSIN S | CTSS, CTSB, CTSZ | CTSS 1/4885CTSK 9/4885CTSL 11/4885 |
| US-20200131198-A1 | Substituted pyrimidinium compounds and derivatives for combating animal pests | THOP1, PNPO, TH | CTSS 2263/4885CTSK 2785/4885CTSL 2794/4885 |
| US-11542280-B2 | Substituted pyrimidinium compounds and derivatives for combating animal pests | THOP1, PNPO, TH | CTSS 2263/4885CTSK 2785/4885CTSL 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.