Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776462 | 0.81 | CTSK (0.40) | CTSKMMP1MMP3MMP9NPSR1 | |
| SCHEMBL4774798 | 0.76 | NOS3 (0.42) | DHODH | |
| SCHEMBL4796492 | 0.75 | TAAR1 (0.42) | DHODH | |
| SCHEMBL4774770 | 0.73 | SPHK1 (0.39) | DHODH | |
| SCHEMBL4791758 | 0.73 | SREBF2 (0.36) | DHODH | |
| SCHEMBL4899444 | 0.69 | MALT1 (0.54) | CTSKBCHE | |
| SCHEMBL4793958 | 0.68 | MEN1 (0.43) | NPSR1SIGMAR1ACACB | |
| SCHEMBL26648602 | 0.67 | MEN1 (0.46) | CTSKMMP1MMP3MMP9SIGMAR1 | |
| SCHEMBL938685 | 0.67 | MAPT (0.53) | CTSKNPSR1SIGMAR1 | |
| SCHEMBL7203913 | 0.67 | MALT1 (0.59) | CTSKSIGMAR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |