Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 3/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774769 | 0.82 | SLC6A2 (0.37) | DHODHTACR3 | |
| SCHEMBL4796492 | 0.77 | TAAR1 (0.42) | DHODHTACR3SREBF2 | |
| SCHEMBL4774798 | 0.77 | NOS3 (0.42) | DHODHMAOBTACR3 | |
| SCHEMBL4774621 | 0.76 | DHODH (0.41) | DHODHTACR3 | |
| SCHEMBL4794671 | 0.74 | HTR1D (0.51) | DHODHMAOB | |
| SCHEMBL4795346 | 0.73 | CTSK (0.41) | DHODH | |
| SCHEMBL4780548 | 0.73 | DHODH (0.39) | DHODHTACR3 | |
| SCHEMBL4791758 | 0.73 | SREBF2 (0.36) | DHODHTRPV1SREBF2 | |
| SCHEMBL4794392 | 0.72 | DHODH (0.36) | DHODHTACR3 | |
| SCHEMBL4795959 | 0.69 | ADRA2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |