Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479289 | 0.95 | RAB9A (0.39) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL3721673 | 0.93 | AURKA (0.37) | RAB9ALMNAMAPK1CYP1A2MAOA | |
| SCHEMBL3721672 | 0.93 | AURKA (0.37) | RAB9ALMNAMAPK1CYP1A2MAOA | |
| SCHEMBL479648 | 0.90 | SENP1 (0.41) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL16752524 | 0.88 | AURKA (0.38) | SENP1PDGFRACSF1RFLT3AURKB | |
| SCHEMBL16752525 | 0.88 | AURKA (0.38) | SENP1PDGFRACSF1RFLT3AURKB | |
| SCHEMBL479345 | 0.86 | LMNA (0.40) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL3153364 | 0.85 | ALDH1A1 (0.43) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL480621 | 0.85 | ALDH1A1 (0.43) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL479748 | 0.83 | AURKA (0.41) | RAB9ALMNAMAPTALDH1A1SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |