SCHEMBL4796638

SCHEMBL4796638

N#CCCN(CCC#N)CCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.43
USP2 O75604 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 2/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM5A P29375 3/20 0.34
NPC1 O15118 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
EYA2 O00167 1/20 0.33
APP P05067 1/20 0.33
ACE P12821 1/20 0.33
PHF8 Q9UPP1 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701701 0.92 LCK (0.38) LCKUSP2HSD17B10ALDH1A1HPGD
SCHEMBL2326430 0.86 ALDH1A1 (0.39) LCKUSP2HSD17B10ALDH1A1HPGD
SCHEMBL12119522 0.84 LCK (0.47) LCKHSD17B10ALDH1A1LMNAMEN1
SCHEMBL5619862 0.81 LCK (0.44) LCKHSD17B10LMNAKMT2AKDM5A
SCHEMBL163128 0.80 LMNA (0.53) LMNAALKBH5SUCNR1EGLN1KDM5A
SCHEMBL12127441 0.79 TDP1 (0.59) LCKUSP2HSD17B10ALDH1A1HPGD
SCHEMBL1344125 0.79 TDP1 (0.56) LCKUSP2HSD17B10ALDH1A1HPGD
SCHEMBL8747264 0.79 CYP1A2 (0.38) ALDH1A1LMNAALKBH5SUCNR1EGLN1
SCHEMBL14342922 0.77 TDP1 (0.53) LMNAALKBH5SUCNR1EGLN1KDM5A
Ammonia Solution, Strong SCHEMBL10538950 0.77 LMNA (0.50) LMNAALKBH5SUCNR1EGLN1KDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323297-B1 Stabilized polynucleotide complexes and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-01-29 US disclosed
EP-0831923-B1 SEPARATION OF ACTIVE COMPLEXES UNIV CALIFORNIA (US) 2006-07-19 EP disclosed
EP-0833667-A4 STABILIZATION OF POLYNUCLEOTIDE COMPLEXES UNIV CALIFORNIA (US) 2001-11-21 EP disclosed
EP-0836645-A4 DRY POWDER FORMULATIONS OF POLYNUCLEOTIDE COMPLEXES UNIV CALIFORNIA (US) 2001-11-21 EP disclosed
EP-0831923-A4 SEPARATION OF ACTIVE COMPLEXES UNIV CALIFORNIA (US) 2000-07-05 EP disclosed
US-5972600-A Separation of active complexes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-10-26 US disclosed
US-5811406-A Dry powder formulations of polynucleotide complexes REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-09-22 US disclosed
EP-0836645-A1 DRY POWDER FORMULATIONS OF POLYNUCLEOTIDE COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-04-22 EP disclosed
EP-0833667-A1 STABILIZATION OF POLYNUCLEOTIDE COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-04-08 EP disclosed
EP-0831923-A1 SEPARATION OF ACTIVE COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-04-01 EP disclosed
WO-1996041873-A1 DRY POWDER FORMULATIONS OF POLYNUCLEOTIDE COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-12-27 WO disclosed
WO-1996040264-A1 SEPARATION OF ACTIVE COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-12-19 WO disclosed
WO-1996040265-A1 STABILIZATION OF POLYNUCLEOTIDE COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-12-19 WO disclosed