Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797971 | 0.83 | KDM4E (0.44) | HSD17B10FLT3KDM4EMAPTDAO | |
| SCHEMBL4795138 | 0.83 | RAB9A (0.46) | HSD17B10FLT3KDM4EMAPTDAO | |
| SCHEMBL4797498 | 0.80 | KDM4E (0.42) | HSD17B10FLT3KDM4EMAPTDAO | |
| SCHEMBL4797332 | 0.75 | MAPT (0.44) | KDM4EMAPTALDH1A1GAAMAPK1 | |
| SCHEMBL3338990 | 0.74 | CA12 (0.48) | KDM4EMAPTALDH1A1GAAMAPK1 | |
| SCHEMBL4801840 | 0.72 | CHEK1 (0.43) | HSD17B10FLT3KDM4EMAPTDAO | |
| SCHEMBL14582115 | 0.65 | CDK5 (0.57) | CDK5CDK5R1NPC1LMNARAB9A | |
| SCHEMBL4782600 | 0.65 | GRM1 (0.51) | KDM4EMAPTALDH1A1GAAMAPK1 | |
| SCHEMBL7880974 | 0.64 | FLT3 (0.56) | HSD17B10FLT3KDM4EMAPTDAO | |
| SCHEMBL29595772 | 0.64 | FLT3 (0.65) | HSD17B10FLT3KDM4EMAPTDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052804-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-08 | — | — | WO | claimed |