Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 3/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 5/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731314 | 0.80 | APOBEC3A (0.33) | APOBEC3AAPOBEC3GPOLQCYP2C9CYP2B6 | |
| SCHEMBL4731297 | 0.78 | TP53 (0.34) | CYP2C9CYP2B6CYP2C19CYP2C8CYP2D6 | |
| SCHEMBL4732780 | 0.73 | NTRK1 (0.34) | APOBEC3AAPOBEC3GABL1BCR | |
| SCHEMBL4731374 | 0.71 | NTRK1 (0.34) | — | |
| SCHEMBL5310626 | 0.67 | ALKBH5 (0.36) | APOBEC3AAPOBEC3G | |
| SCHEMBL5372491 | 0.64 | NPSR1 (0.39) | CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL5372495 | 0.64 | GRM5 (0.37) | APOBEC3AAPOBEC3GABL1BCRKIT | |
| SCHEMBL4731299 | 0.63 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GABL1KDRFGFR1 | |
| SCHEMBL1348539 | 0.62 | KDM4E (0.49) | APOBEC3AAPOBEC3GCYP1A2CYP3A4BRAF | |
| SCHEMBL4732771 | 0.62 | APOBEC3A (0.34) | APOBEC3AAPOBEC3GCYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |