Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4795631 | 0.89 | ESR2 (0.32) | ESR2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL5872683 | 0.75 | CHRNB2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL4796462 | 0.74 | ESR2 (0.32) | ESR2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL4799670 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL2778334 | 0.69 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL27670353 | 0.65 | ESR2 (0.36) | ESR2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL1034641 | 0.63 | ESR2 (0.32) | ESR2CYP2A6CYP2B6 | |
| SCHEMBL2968566 | 0.62 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL4004708 | 0.62 | ADRA1A (0.32) | — | |
| SCHEMBL27757694 | 0.62 | ESR2 (0.36) | ESR2CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432336-B2 | Metallocene catalyst for propylene copolymers with ethylene | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-10-07 | — | — | US | claimed |
| US-7432336-B2 | Metallocene catalyst for propylene copolymers with ethylene | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1615961-A1 | CATALYSTS FOR PROPYLENE COPOLYMERS, POLYMERIZATION PROCESS AND COPOLYMER OF PROPYLENE | ExxonMobil Chemical Patents Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004094490-A1 | CATALYSTS FOR PROPYLENE COPOLYMERS, POLYMERIZATION PROCESS AND COPOLYMER OF PROPYLENE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| US-20040210013-A1 | Metallocene catalyst for propylene copolymers with ethylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-10-21 | — | — | US | disclosed |