Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4798649 | 0.75 | ESR2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4088340 | 0.73 | CHRNB2 (0.35) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL3685419 | 0.73 | CHRNB2 (0.35) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL4089006 | 0.73 | CHRNB2 (0.35) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL5872685 | 0.73 | CHRNB2 (0.36) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL27488712 | 0.72 | CHRNB2 (0.34) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8426993 | 0.72 | CHRNB2 (0.34) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL3190099 | 0.72 | CHRNB2 (0.35) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL4795631 | 0.72 | ESR2 (0.32) | — | |
| SCHEMBL6930673 | 0.71 | CHRNB2 (0.36) | CHRNB2CHRNA4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105608-B2 | Copolymer of propylene with a conjugated diene and a process of preparing the same | TONEN CHEMICAL CORPORATION (JP) | 2006-09-12 | — | — | US | disclosed |
| US-20050154139-A1 | Copolymer of propylene with a conjugated diene and a process of preparing the same | TONEN CHEMICAL CORPORATION (JP) | 2005-07-14 | — | — | US | disclosed |