Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401297 | 0.78 | CYP3A4 (0.48) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29789973 | 0.78 | CYP3A4 (0.48) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28414737 | 0.77 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL19130510 | 0.77 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL1258715 | 0.74 | CYP3A4 (0.52) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29383293 | 0.74 | CYP3A4 (0.52) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28408574 | 0.73 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL29428992 | 0.71 | MAPT (0.70) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2980211 | 0.71 | MAPT (0.70) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL10775408 | 0.70 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332260-B2 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | CORNING INCORPORATED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1114043-B1 | NAPHTHOPYRANS ANNELATED IN C 6?-C 7?, THEIR PREPARATION AND COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM | CORNING INC (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-1119560-B1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING SA (FR) | 2003-03-05 | — | — | EP | disclosed |
| US-6506538-B1 | Ophthalmic lenses, contact lenses, solar protection glasses, filters, camera optics or photographic apparatus optics or other optical devices | CORNING S.A. (FR) | 2003-01-14 | — | — | US | disclosed |
| US-20020197562-A1 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | BREYNE OLIVIER (FR) | 2002-12-26 | — | — | US | disclosed |
| EP-1119560-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | Corning S.A. (FR) | 2001-08-01 | — | — | EP | disclosed |
| US-6207084-B1 | PHOTOCHROMIC COMPOSITIONS AND PHOTOCHROMIC OPHTHALMIC ARTICLES (LENSES FOR EXAMPLE) WHICH CONTAIN SAID NAPHTHOPYRANS | CORNING S.A. (FR) | 2001-03-27 | — | — | US | disclosed |
| WO-2000015628-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020197562-A1 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | C5, CCNC, C9 | MAPT 2510/4885KDM4E 1929/4885ALDH1A1 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.