Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799682 | 0.88 | PTGS1 (0.50) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL12611966 | 0.83 | PTGS1 (0.49) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL14930314 | 0.82 | PTGS1 (0.54) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL4799906 | 0.80 | PTGS1 (0.46) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL2012004 | 0.80 | HIF1A (0.46) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL2562052 | 0.78 | XDH (0.50) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL14925941 | 0.78 | PTGS1 (0.50) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL4801084 | 0.77 | PTGS1 (0.42) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL2558890 | 0.76 | PTGS1 (0.46) | PTGS1PTGS2XDHHIF1AEPAS1 | |
| SCHEMBL4809948 | 0.76 | PTGS1 (0.42) | PTGS1PTGS2XDHHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |
| US-20050203145-A1 | 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203145-A1 | 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | ALOX5, LOX, ALOX15 | PTGS1 36/4885PTGS2 31/4885XDH 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.